美国德州农工大学2025年博士后招聘（数学建模-埃及伊蚊的基因驱动系统）

Postdoc: mathematical modeling-gene drive systems in Aedes aegypti mosquito

Texas A&M University - College of Veterinary Medicine & Biomedical Sciences - Department of Veterinary Integrative Biosciences

Date Posted: Posted on 15 July 2025

Location: United States (US)

Job Tags:

mathematical model, mosquitoes

Postdoctoral: mathematical modeling of gene drive systems in Aedes aegypti mosquitoes

We have funding for a project titled: “Improving gene drive efficiency in Aedes aegypti

mosquitoes through novel target site selection.” Aedes aegypti is the primary vector of dengue,

Zika, chikungunya, and urban yellow fever. We are searching for a postdoc to work on the

modeling aspects of the project. The project is a collaboration between the Myles Lab

https://tamu.edu/myles-lab/ and the Ndeffo Lab https://vibs.tamu.edu/MartialNdeffo.

Research project will investigate an innovative strategy to improve gene drive efficiency in

Aedes aegypti mosquitoes through novel target site selection, an approach not previously

studied in this species. Specifically, we will investigate the potential of targeting a haplolethal

gene for effective genetic control of Ae. aegypti populations. The modeling aspect of the

project will focus on developing computational models to analyze the intricate dynamics of a

homing rescue drive targeting haplolethal gene in Aedes aegypti mosquito populations.

Additionally, it will evaluate the efficacy (ecological and epidemiological) of various drive

mechanisms based on this platform, including population replacement strategies, population

suppression approaches, and toxin-antidote systems.

The postdoc responsibilities will include, among others:

• Working with molecular biologists to develop and parameterize models of genetic

control systems

• Calibrating epidemiological models to available mosquito-borne disease data

• Contributing to related research on vector-borne diseases modeling.

The ideal candidate should have 1) a strong background in applied mathematical sciences,

computer science, or any other quantitative field, 2) experience with population biology,

population genetics, or ecological and epidemiological modeling, and 3) an interest in

mosquitoes and/or mosquito-borne diseases. The candidate should have demonstrably strong

programming skills in R or Python, and the ability to work independently and execute research

projects with minimal supervision. Good communication skills demonstrated by past

productivity including peer- reviewed publications and/or other scientific and technical output is

required for the position. Prior experience with vector-borne disease modeling will be a plus.

Review of applications will begin immediately, and the position will remain open until filled. The

position is available for a maximum of two years. Appointment will be made on a yearly basis,

renewable based on availability of funds. A competitive salary will be commensurate with

experience. The position comes with a standard benefits package available at Texas A&M

University.

Applications should include a CV, statement of research interests, copies of recent publications

(relevant to the position), the contact of two references and be e-mailed as a single pdf file to

m.ndeffo@tamu.edu. Only selected applicants will be contacted. Incomplete applications will not

be considered.

Texas A&M University is an Equal Opportunity/Affirmative Action/ Veterans/Disable Employer

Tagged as: Mathematics